An article, “What does "appropriate scientific justification" mean for the review of human pluripotent stem cell, embryo, and related research?” was published in Stem Cell Reports. (Muto K.)

Jonlin EC, Fujita M, Isasi R, Kato K, Munsie M, Muto K, Niakan K, Saha K, Sugarman J, Turner L, Hyun I.

What does "appropriate scientific justification" mean for the review of human pluripotent stem cell, embryo, and related research? Stem Cell Reports. 2025 Apr 17:102479.

https://doi.org/10.1016/j.stemcr.2025.102479 Epub ahead of print.
https://linkinghub.elsevier.com/retrieve/pii/S2213-6711(25)00083-9

[Summary]

This article complements the 2021 International Society for Stem Cell Research (ISSCR) Guidelines for Stem Cell Research and Clinical Translation by explaining what “adequate and appropriate scientific justification” means for human pluripotent stem cell, embryo, and related research, thus providing practical advice for review and oversight bodies, regulators, and investigators who conduct research in these areas.

Notes:

Japanese language version of ISSCR (International Society for Stem Cell Research) 2021 Guidelines for Stem Cell Research and Clinical Translation was published in March 2023. Some members of our department collaborated on the translation.